Medphen ABV PEEK
First choice material for demanding healthcare applications, it incorporates graphite oxide reinforcement with silver particles. The ABV PEEK polymer provides long-term performance up to 255°C, with exceptional chemical resistance, and high resistance to wear and abrasion.
Graphite-based material additives (GBMs) enhance the following properties:
- ABV PEEK contains GO-AgNPs, powerful antibacterial, and antiviral. It inhibits the growth of algae, fungi, and mold.
- Increases abrasion resistance and good weathering
- Resistance to lipids, cleaning and disinfectant agents
Solvay Specialty Polymers is the manufacturer of the base polymer used as a matrix, which is added to the graphite-based material and silver particles.
- In Medical Device applications with USP Class VI plastics and ISO 10993-1 certification, biocompatibility up to 30 days in contact with the human body.
- Medical device Housing, respiratory devices: elements or spare parts Its use is suitable for food contact according to EU Directive No 10/2011 and FDA Regulation 21 CFR.
The use in a given application or product must be tested to determine its performance in advance. The user responsible for the design must confirm the product requirements.
Recommendations for use
- Processing temperature range: 390-420 ° C
- Recommended bed temperature: > 200 ° C
- Drying conditions: 150 ° C for at least 4 hours
- Nozzle size: 0.4 - 0.6 mm To prevent excessive wear on extrusion components, special hardened or stainless steel nozzles should be used.
Place the filament in the sealed bag with the desiccant that comes incorporated after each use.
General Description of Antimicrobial (ABV)
Graphene oxide is a material belonging to the family of graphene-based materials (GBM). Although in itself it has a weak bactericidal effect, in conjunction with silver particles, better results are obtained than for both materials separately. In this case, the GO film contains the particles attached to their functional groups. The high specific surface area of GO facilitates an attractive interaction to the bacterial membrane with a high degree of contact and allows the silver particles to release Ag+ ions on the bacteria in a localized manner. These ions generate ROS, which in turn destroy the respiratory system of the bacteria.
Steps of antimicrobial action: (A) AgNPs diffusion and uptake into the bacterial cell: Accumulation and dissolution of AgNPs at plasma membrane cause cell leakage. (B) Destabilization of Ribosomes: denatures ribosomes inhibiting protein synthesis and plasma membrane degradation. (C) Enzyme interaction: AgNPs bind with the thiol group (-SH) in the respiratory enzymes and deactivate them. (D) Interruption of electron transfer chain: AgNPs interfere with electron transport affecting the signaling pathway. (E) Reactive oxygen species (ROS): Mitochondrial damage induces ROS which oxidizes proteins. (F) DNA Damage. AgNPs binds with DNA preventing its replication and multiplication causing apoptosis. (G) Cell Death: Formation of pits and perforations in the cell membrane leads to the release of cell organelles and cell death.